Long non-coding RNA TUG1 promotes colorectal cancer metastasis via EMT pathway

@inproceedings{Wang2016LongNR,
  title={Long non-coding RNA TUG1 promotes colorectal cancer metastasis via EMT pathway},
  author={Liang Toon Wang and Zhenxian Zhao and Weidong Feng and Zhijun Ye and Weigang Dai and Changhua Zhang and Jianjun Peng and Kaiming Wu},
  booktitle={Oncotarget},
  year={2016}
}
Colorectal cancer (CRC) is the third most common malignancy in developed countries, and its incidence rate has been continuously increasing in developing countries over the past few decades. Taurine-upregulated gene 1 (TUG1) plays an important role in signal transduction, regulation of cell morphology, migration, proliferation and apoptosis. The aim of the present study was to evaluate the role of TUG1 in CRC, and whether knockdown of TUG1 expression could affect cell proliferation, migration… CONTINUE READING

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