Long non-coding RNA TPTEP1 inhibits hepatocellular carcinoma progression by suppressing STAT3 phosphorylation

  title={Long non-coding RNA TPTEP1 inhibits hepatocellular carcinoma progression by suppressing STAT3 phosphorylation},
  author={Hongda Ding and Junpeng Liu and Ruoyao Zou and P.-T. Cheng and Yang Su},
  journal={Journal of Experimental \& Clinical Cancer Research : CR},
  • Hongda Ding, Junpeng Liu, Yang Su
  • Published 9 May 2019
  • Biology, Medicine, Chemistry
  • Journal of Experimental & Clinical Cancer Research : CR
BackgroundHepatocellular carcinoma (HCC) is still the most common cause of tumor-related death worldwide and accumulating studies report that long non-coding RNAs (LncRNAs) are closely related with HCC development, metastasis and prognosis. Cisplatinum, a well-known chemotherapeutic drug, has been widely used for treatment of numerous human cancers including HCC. This study aimed to investigate the differential expressions of LncRNAs in HCC cells treated with cisplatinum and its underlying… 
Long non-coding RNA TPTEP1 exerts inhibitory effects on hepatocellular carcinoma by impairing microRNA-454-3p-mediated DLG5 downregulation.
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