Long non-coding RNA MALAT-1 contributes to maintenance of stem cell-like phenotypes in breast cancer cells

@inproceedings{Zeng2018LongNR,
  title={Long non-coding RNA MALAT-1 contributes to maintenance of stem cell-like phenotypes in breast cancer cells},
  author={Linghuan Zeng and Ying xin Cen and Jun-jie Chen},
  booktitle={Oncology letters},
  year={2018}
}
Due to the accumulating evidence that has demonstrated the vital role of cancer stem cells (CSCs) in tumor initiation, progression and metastasis, the mechanisms that maintain the stemness of CSCs have attracted increasing attention. Metastasis-associated lung adenocarcinoma transcript-1 (MALAT-1), a long non-coding RNA, which has been revealed to be associated with the malignant behavior of tumors, performs a critical role in maintaining the stemness in several CSCs. In the present study, it… CONTINUE READING
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