Long non-coding RNA FTH1P3 facilitates uveal melanoma cell growth and invasion through miR-224-5p

  title={Long non-coding RNA FTH1P3 facilitates uveal melanoma cell growth and invasion through miR-224-5p},
  author={X. Zheng and H. Tang and X. Zhao and Yamei Sun and Y. Jiang and Y. Liu},
  journal={PLoS ONE},
  • X. Zheng, H. Tang, +3 authors Y. Liu
  • Published 2017
  • Biology, Medicine
  • PLoS ONE
  • Growing evidences indicated that Long noncoding RNAs (lncRNAs) played important roles in tumor initiation and progression. However, the function and mechnism of lncRNA ferritin heavy chain 1 pseudogene 3 (FTH1P3) remain unknown in uveal melanoma. We showed that the expression level of FTH1P3 was upregulated in uveal melanoma cell lines and tissues. Elevated expression of FTH1P3 promoted uveal melanoma cell proliferation, cell cycle and migration. Moreover, we found that FTH1P3 was a direct… CONTINUE READING
    34 Citations

    Figures and Topics from this paper

    Long Noncoding RNA PVT1 Silencing Prevents the Development of Uveal Melanoma by Impairing MicroRNA-17-3p-Dependent MDM2 Upregulation.
    • 10
    • PDF
    Long non-coding RNA FTH1P3 regulated metastasis and invasion of esophageal squamous cell carcinoma through SP1/NF-kB pathway.
    • Lijun Yang, K. Sun, +6 authors F. He
    • Biology, Medicine
    • Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
    • 2018
    • 23
    Long non-coding RNA FTH1P3 promotes the metastasis and aggressiveness of non-small cell lung carcinoma by inducing epithelial-mesenchymal transition.
    • Zhengxiong Li, Yadi Wang
    • Medicine, Biology
    • International journal of clinical and experimental pathology
    • 2019
    • 2
    • PDF
    CircPCMTD1 Acts as the Sponge of miR-224-5p to Promote Glioma Progression
    • 13
    • PDF
    lncRNA NEAT1 facilitates melanoma cell proliferation, migration, and invasion via regulating miR‐495‐3p and E2F3
    • 21


    Long noncoding RNA CCAT1 promotes hepatocellular carcinoma progression by functioning as let-7 sponge
    • 202