Long-lived positron emitters zirconium-89 and iodine-124 for scouting of therapeutic radioimmunoconjugates with PET.

@article{Verel2003LonglivedPE,
  title={Long-lived positron emitters zirconium-89 and iodine-124 for scouting of therapeutic radioimmunoconjugates with PET.},
  author={Iris Verel and Gerard W. M. Visser and Otto C Boerman and Julliette E M van Eerd and Ron Finn and Ronald Boellaard and Maria J. W. D. Vosjan and Marijke Stigter-van Walsum and Gordon B J Snow and Guus A. M. S. van Dongen},
  journal={Cancer biotherapy & radiopharmaceuticals},
  year={2003},
  volume={18 4},
  pages={655-61}
}
Antibody-PET imaging might be of value for the selection of radioimmunotherapy (RIT) candidates to confirm tumor targeting and to estimate radiation doses to tumor and normal tissues. One of the requirements to be set for such a scouting procedure is that the biodistributions of the diagnostic and therapeutic radioimmunoconjugates should be similar. In the present study we evaluated the potential of the positron emitters zirconium-89 ((89)Zr) and iodine-124 ((124)I) for this approach, as these… CONTINUE READING
52 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 52 extracted citations

Similar Papers

Loading similar papers…