Long-lasting sensitization of reward-directed behavior by amphetamine.

  title={Long-lasting sensitization of reward-directed behavior by amphetamine.},
  author={I. A. Guzm{\'a}n M{\'e}ndez and Matthew T Williams and Atasi Bhavsar and Annie P Lu and Jennifer L. Bizon and Barry Setlow},
  journal={Behavioural brain research},
  volume={201 1},
Exposure to psychostimulant drugs of abuse such as amphetamine can result in long-lasting "sensitization" of reward-directed behavior, such that subjects display enhancements in behavior directed by and toward rewards and reward-predictive cues (i.e. "incentive sensitization"). The purpose of these experiments was to determine the degree to which such sensitization resulting from chronic amphetamine exposure influences both appetitive and consummatory food-motivated behavior. Adult male Long… CONTINUE READING

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