Long-lasting reduction of Brugia timori microfilariae following a single dose of diethylcarbamazine combined with albendazole.

@article{Fischer2003LonglastingRO,
  title={Long-lasting reduction of Brugia timori microfilariae following a single dose of diethylcarbamazine combined with albendazole.},
  author={Philipp E. Fischer and Yenny Djuardi and Is Suhariah Ismid and Paul R{\"u}ckert and Mark Bradley and Taniawati Supali},
  journal={Transactions of the Royal Society of Tropical Medicine and Hygiene},
  year={2003},
  volume={97 4},
  pages={
          446-8
        }
}
The long-term effect of a single oral dose of 6 mg/kg bodyweight of diethylcarbamazine (DEC) combined with 400 mg albendazole (ALB) on the microfilariae (mf) of the lymphatic filarial parasite Brugia timori was studied on Alor island, Indonesia from April 2001 to April 2002. Before treatment the geometric mean of the mf density in 96 infected study subjects was 150 mf/mL night blood (range 1-5696 mf/mL). One year after treatment 69 subjects (72%) were mf-negative and the overall geometric mean… CONTINUE READING