Long-lasting contact urticaria. Type I and type IV allergy from castor bean and a hypothesis of systemic IgE-mediated allergic dermatitis.

Abstract

A unique urticarial type I patch-test reaction to castor bean that persisted for more than 48 hours and was followed by a delayed type IV reaction is described. Immunohistochemical and electron microscopic observations indicated involvement of eosinophils and IgE receptors on Langerhans' cells. The authors present a scheme for the role of Langerhans' cells in skin allergy.

Cite this paper

@article{Kanerva1990LonglastingCU, title={Long-lasting contact urticaria. Type I and type IV allergy from castor bean and a hypothesis of systemic IgE-mediated allergic dermatitis.}, author={Lasse Kanerva and Tuula Estlander and Riitta Jolanki}, journal={Dermatologic clinics}, year={1990}, volume={8 1}, pages={181-8} }