Long lasting consequences of cannabis exposure in adolescence

  title={Long lasting consequences of cannabis exposure in adolescence},
  author={T. Rubino and D. Parolaro},
  journal={Molecular and Cellular Endocrinology},
  • T. Rubino, D. Parolaro
  • Published 2008
  • Medicine
  • Molecular and Cellular Endocrinology
  • Despite the increasing use of cannabis among adolescents, there are little and often contradictory studies on the long-term neurobiological consequences of cannabis consumption in juveniles. Adolescence is a critical phase for cerebral development, where the endocannabinoid system plays an important role influencing the release and action of different neurotransmitters. Therefore, a strong stimulation by the psychoactive component of marijuana, delta-9-tetrahydrocanabinol (THC), might lead to… CONTINUE READING
    129 Citations

    Tables and Topics from this paper

    Adolescent cannabis exposure interacts with mutant DISC1 to produce impaired adult emotional memory
    • 26
    Chronic exposure to cannabinoids during adolescence causes long‐lasting behavioral deficits in adult mice
    • 25
    Adolescent brain maturation, the endogenous cannabinoid system and the neurobiology of cannabis-induced schizophrenia
    • 249
    • PDF
    Endocannabinoids in brain plasticity: Cortical maturation, HPA axis function and behavior
    • 35


    Chronic Δ9-Tetrahydrocannabinol During Adolescence Provokes Sex-Dependent Changes in the Emotional Profile in Adult Rats: Behavioral and Biochemical Correlates
    • 254
    • PDF
    Adolescent exposure to cannabinoids induces long-Lasting changes in the response to drugs of abuse of rat midbrain dopamine neurons
    • 170
    • PDF
    Short-term memory impairment in cannabis-dependent adolescents.
    • 180
    Chronic cannabinoid exposure produces lasting memory impairment and increased anxiety in adolescent but not adult rats
    • 272
    • PDF
    Cannabinoids and gene expression during brain development
    • 88
    Cannabis use and psychosocial adjustment in adolescence and young adulthood.
    • 493
    The adolescent brain and age-related behavioral manifestations
    • L. Spear
    • Psychology, Medicine
    • Neuroscience & Biobehavioral Reviews
    • 2000
    • 4,490
    • PDF