Long-lasting change in 5-HT2A receptor-mediated behavior in rats after a single footshock.

Abstract

To investigate the long-term functional change in the 5-HT(2A) receptor after acute stress, we examined the effect of single footshock on head shake behavior induced by the 5-HT(2A) receptor agent (+/-)-2,5-dimethoxy-4-iodoamphetamine hydrochloride (DOI) in rats. Head shakes were evoked in a dose-dependent manner by 0.1-10 mg/kg of DOI, and the maximal… (More)

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@article{Izumi2002LonglastingCI, title={Long-lasting change in 5-HT2A receptor-mediated behavior in rats after a single footshock.}, author={Takeshi Izumi and Katsuji Suzuki and Takeshi Inoue and Xiaobai Li and Yuji Maki and Ihoko Muraki and Yuji Kitaichi and Syogo Hashimoto and Tsukasa Koyama}, journal={European journal of pharmacology}, year={2002}, volume={452 2}, pages={199-204} }