Long lasting IgG subclass and antibacterial polysaccharide antibody deficiency after allogeneic bone marrow transplantation.

@article{Aucouturier1987LongLI,
  title={Long lasting IgG subclass and antibacterial polysaccharide antibody deficiency after allogeneic bone marrow transplantation.},
  author={P. Aucouturier and Anne Laure Barra and Liliane Intrator and Catherine Cordonnier and Dominique Schulz and F. A. Moura Duarte and J. P. Vernant and J. L. Preud'homme},
  journal={Blood},
  year={1987},
  volume={70 3},
  pages={779-85}
}
Serum IgG subclasses were measured by a competitive indirect immunoassay with monoclonal antibodies in 31 leukemic patients before and after bone marrow transplantation. Antibodies to Hemophilus influenzae type b (Hib) capsular polysaccharide were determined in 28 cases. Abnormally low or borderline subclass (mostly IgG2 and IgG4) levels were found late after transplant in 23 infected and noninfected patients. These levels persisted for as long as 25 months, in association with low or… CONTINUE READING