Long-acting contraceptive agents: Design of the who chemical synthesis programme

@article{Crabb1983LongactingCA,
  title={Long-acting contraceptive agents: Design of the who chemical synthesis programme},
  author={P. Crabb{\'e} and S. Archer and G. Benagiano and E. Diczfalusy and Takeru Higuchi},
  journal={Steroids},
  year={1983},
  volume={41},
  pages={243-253}
}
  • P. Crabbé, S. Archer, +2 authors Takeru Higuchi
  • Published 1983
  • Medicine
  • Steroids
  • The great demand for improved long-acting injectable steroid contraceptives, particularly in developing countries, and the relative lack of interest from the pharmaceutical industry to develop such products stimulated WHO to launch a synthetic and screening programme to find improved, safe and acceptable injectable preparations. More than 210 esters of norethisterone (17 alpha-ethynyl-17 beta-hydroxyestr-4-en-3-one) and levonorgestrel (D-(-)-13 beta-ethyl-17 alpha-ethynyl-17 beta-hydroxygon-4… CONTINUE READING
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