Long-Term Transfer and Expression of the Human b-Globin Gene in a Mouse Transplant Model

Abstract

Somatic gene therapy of hemoglobinopathies depends inikb human b-globin gene-containing provirus in 2 of these mice. In addition, long-term expression of the transferred tially on the demonstration of safe, efficient gene transfer and long-term, high-level expression of the transferred hugene is seen in 2 mice at levels of 5% and 20% that of endogenous… (More)

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Cite this paper

@inproceedings{Raftopoulos1997LongTermTA, title={Long-Term Transfer and Expression of the Human b-Globin Gene in a Mouse Transplant Model}, author={Harry Raftopoulos and Maureen Ward and Philippe Leboulch}, year={1997} }