Long-Term Population-Based Cerebral Ischemic Event and Cognitive Outcomes of Direct Oral Anticoagulants Compared With Warfarin Among Long-term Anticoagulated Patients for Atrial Fibrillation.

@article{Jacobs2016LongTermPC,
  title={Long-Term Population-Based Cerebral Ischemic Event and Cognitive Outcomes of Direct Oral Anticoagulants Compared With Warfarin Among Long-term Anticoagulated Patients for Atrial Fibrillation.},
  author={Victoria R. Jacobs and Heidi T May and Tami L. Bair and Brian G. Crandall and Michael Cutler and JoannaM. Day and Charles Mallender and Jeffrey S. Osborn and Scott M. Stevens and Jeffrey P. Weiss and Scott C. Woller and Thomas Jared Bunch},
  journal={The American journal of cardiology},
  year={2016},
  volume={118 2},
  pages={
          210-4
        }
}
Direct oral anticoagulants (DOACs) have been used in clinical practice in the United States for the last 4 to 6 years. Although DOACs may be an attractive alternative to warfarin in many patients, long-term outcomes of use of these medications are unknown. We performed a propensity-matched analysis to report patient important outcomes of death, stroke/transient ischemic attack (TIA), bleeding, major bleeding, and dementia in patients taking a DOAC or warfarin. Patients receiving long-term… CONTINUE READING
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