Long-Term Neuroinflammation Induced by Influenza A Virus Infection and the Impact on Hippocampal Neuron Morphology and Function.

@article{Hosseini2018LongTermNI,
  title={Long-Term Neuroinflammation Induced by Influenza A Virus Infection and the Impact on Hippocampal Neuron Morphology and Function.},
  author={Shirin Hosseini and Esther Wilk and Kristin Michaelsen-Preusse and Ingo Gerhauser and Wolfgang Baumgaertner and Robert Geffers and Klaus Schughart and Martin Korte},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2018},
  volume={38 12},
  pages={3060-3080}
}
Acute influenza infection has been reported to be associated with neurological symptoms. However, the long-term consequences of an infection with neurotropic and non-neurotropic influenza A virus (IAV) variants for the CNS remain elusive. We can show that spine loss in the hippocampus after infection with neurotropic H7N7 (rSC35M) and non-neurotropic H3N2 (maHK68) in female C57BL/6 mice persists well beyond the acute phase of the disease. Although spine number was significantly reduced at 30 d… CONTINUE READING
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