Long-Term Fish Oil Supplementation Induces Cardiac Electrical Remodeling by Changing Channel Protein Expression in the Rabbit Model

@inproceedings{Xu2010LongTermFO,
  title={Long-Term Fish Oil Supplementation Induces Cardiac Electrical Remodeling by Changing Channel Protein Expression in the Rabbit Model},
  author={Xulin Xu and Min Jiang and Yuhong Wang and Timothy Smith and Clive Marc Baumgarten and M. A. Wood and G N Tseng},
  booktitle={PloS one},
  year={2010}
}
Clinical trials and epidemiological studies have suggested that dietary fish oil (FO) supplementation can provide an anti-arrhythmic benefit in some patient populations. The underlying mechanisms are not entirely clear. We wanted to understand how FO supplementation (for 4 weeks) affected the action potential configuration/duration of ventricular myocytes, and the ionic mechanism(s)/molecular basis for these effects. The experiments were conducted on adult rabbits, a widely used animal model… CONTINUE READING

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2 Excerpts

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