Long-Term Efficacy and Safety of Tretinoin Emollient Cream 0.05% in the Treatment of Photodamaged Facial Skin

@article{Kang2005LongTermEA,
  title={Long-Term Efficacy and Safety of Tretinoin Emollient Cream 0.05\% in the Treatment of Photodamaged Facial Skin},
  author={Sewon Kang and W. Bergfeld and A. Gottlieb and J. Hickman and J. Humeniuk and S. Kempers and M. Lebwohl and N. Lowe and A. McMichael and J. Milbauer and T. Phillips and J. Powers and D. Rodriguez and R. Savin and J. Shavin and D. Sherer and N. Silvis and R. Weinstein and J. Weiss and C. Hammerberg and G. Fisher and M. Nighland and R. Grossman and J. Nyirady},
  journal={American Journal of Clinical Dermatology},
  year={2005},
  volume={6},
  pages={245-253}
}
AbstractBackground: Long-term (>1 year) placebo-controlled studies of tretinoin in the treatment of photodamaged skin have not been conducted. Recently, we conducted a 2-year placebo-controlled study of tretinoin emollient cream 0.05%, including histopathologic assessment of safety and analysis of markers of collagen deposition. Objective: The objective of the study was to determine the long-term safety and efficacy of tretinoin emollient cream 0.05% in the treatment of moderate to severe… Expand
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