Long-Term Asymmetrical Acceleration of Protein Evolution after Gene Duplication

@inproceedings{Rosell2014LongTermAA,
  title={Long-Term Asymmetrical Acceleration of Protein Evolution after Gene Duplication},
  author={Oriol Pich i Rosell{\'o} and Fyodor A. Kondrashov},
  booktitle={Genome biology and evolution},
  year={2014}
}
Rapid divergence of gene copies after duplication is thought to determine the fate of the copies and evolution of novel protein functions. However, data on how long the gene copies continue to experience an elevated rate of evolution remain scarce. Standard theory of gene duplications based on some level of genetic redundancy of gene copies predicts that the period of accelerated evolution must end relatively quickly. Using a maximum-likelihood approach we estimate preduplication, initial… CONTINUE READING
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