Long Noncoding RNAs in Cardiovascular Pathology, Diagnosis, and Therapy.

  title={Long Noncoding RNAs in Cardiovascular Pathology, Diagnosis, and Therapy.},
  author={Christian B{\"a}r and Shambhabi Chatterjee and Thomas Thum},
  volume={134 19},
Vast parts of mammalian genomes encode for transcripts that are not further translated into proteins. The purpose of the majority of such noncoding ribonucleic acids (RNAs) remained paradoxical for a long time. However, a growing body of evidence demonstrates that long noncoding RNAs are dynamically expressed in different cell types, diseases, or developmental stages to execute a wide variety of regulatory roles at virtually every step of gene expression and translation. Indeed, long noncoding… CONTINUE READING
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