Long Noncoding RNA DANCR Is a Positive Regulator of Proliferation and Chondrogenic Differentiation in Human Synovium-Derived Stem Cells.

@article{Zhang2017LongNR,
  title={Long Noncoding RNA DANCR Is a Positive Regulator of Proliferation and Chondrogenic Differentiation in Human Synovium-Derived Stem Cells.},
  author={Lei Zhang and Chao Yang and Shuo Chen and Guihua Wang and Ben Shi and Xin Tao and Liwu Zhou and Jianning Zhao},
  journal={DNA and cell biology},
  year={2017},
  volume={36 2},
  pages={
          136-142
        }
}
Cartilage tissues have limited capacity for repair after damage and then cause osteoarthritis, so finding alternative treatment is ongoing. Mesenchymal stem cells (MSCs) have become a promising therapy for cartilage damage and diseases due to the advantages of easy separation, high proliferative potentiality, and genetic stability. Synovium-derived MSCs (SMSCs) have been recognized as an ideal source for cartilage repair. In our previous study, we found that Sox4 promoted proliferation and… CONTINUE READING

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