Long-Chain Fatty Acid Combustion Rate Is Associated with Unique Metabolite Profiles in Skeletal Muscle Mitochondria

Abstract

BACKGROUND/AIM Incomplete or limited long-chain fatty acid (LCFA) combustion in skeletal muscle has been associated with insulin resistance. Signals that are responsive to shifts in LCFA beta-oxidation rate or degree of intramitochondrial catabolism are hypothesized to regulate second messenger systems downstream of the insulin receptor. Recent evidence… (More)
DOI: 10.1371/journal.pone.0009834

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Cite this paper

@inproceedings{Seifert2010LongChainFA, title={Long-Chain Fatty Acid Combustion Rate Is Associated with Unique Metabolite Profiles in Skeletal Muscle Mitochondria}, author={Erin L. Seifert and Oliver Fiehn and V{\'e}ronic B{\'e}zaire and David R. Bickel and Gert Wohlgemuth and Sean H Adams and Mary-Ellen Harper}, booktitle={PloS one}, year={2010} }