Long‐term follow‐up of living kidney donors: a longitudinal study

@article{ElAgroudy2007LongtermFO,
  title={Long‐term follow‐up of living kidney donors: a longitudinal study},
  author={Amgad E. El-Agroudy and Alaa A. Sabry and Ehab Wahba Wafa and Ahmed H Neamatalla and Amani Mostafa Ismail and Tarek A. Mohsen and Abdalla Khalil and Ahmed A. Shokeir and Mohamed A. Ghoneim},
  journal={BJU International},
  year={2007},
  volume={100}
}
To analyse retrospectively the general health status and renal and cardiovascular consequences of living‐related kidney donation, as the long‐term effects of unilateral nephrectomy for kidney donation are of particular interest with the currently increasing practice of living‐donor transplantation. 
Hypertension, Cardiovascular Episodes And Lipid Profile In Living Kidney Donors In Poland - Single Centre Experience
TLDR
The objective of the study was to evaluate hypertension, cardiovascular disease and lipid profile in living kidney donors after open nephrectomies which were performed between 1995 and 2005 in this institution.
Evaluation of Potential Living Kidney Donors
TLDR
The incidence of ESRD is increasing, as a result of the increase in diabetes as well as other CKD causes, however the rise in E SRD is not matched by a rise in available kidneys for transplantation.
Outcome of the living kidney donor.
  • P. Delanaye, L. Weekers, +4 authors J. Krzesinski
  • Medicine
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
  • 2012
TLDR
The consequences of kidney donation on the living donor health are reviewed, considering very shortterm (linked to the surgery), short term (effect of nephrectomy on glomerular filtration rate) and long term (risk of mortality, chronic kidney disease, proteinuria and hypertension) consequences of kidneys donation.
More than a decade after live donor nephrectomy: a prospective cohort study
TLDR
Kidney function appears stable, and hypertension does not seem to occur more frequently compared to the general population, and donor outcomes are excellent 10 years post‐donation.
Living kidney donor transplants over a 16-year period in South Africa: a single center experience.
TLDR
There is a need to encourage living kidney donation, especially amongst the Black populations, and to emphasize the value and significance of post-donation follow-up visits to all potential donors.
Comparison of Medium-term Outcomes of Living Kidney Donors With Longitudinal Healthy Control in the United Kingdom
TLDR
The medium-term morbidity and mortality outcomes of live donors in comparison with a healthy cohort suggest that live donation is not associated with excess mortality, end-stage renal disease, or morbidity, in at least 10 years follow-up.
Long-term Outcomes of Living Kidney Donation
TLDR
Living kidney donation appears to be associated with a small absolute increase in risk of end-stage renal disease, hypertension, and pregnancy complications, such as preeclampsia and gestational hypertension.
Medical Evaluation of the Living Kidney Donor
TLDR
This chapter seeks to provide a comprehensive approach to the counseling and medical evaluation of potential living donor based on a critical review of the available scientific literature on potentially adverse risk factors.
Investigating kidney donation as a risk factor for hypertension and microalbuminuria: findings from the Swiss prospective follow-up of living kidney donors
TLDR
Nephrectomy propagates hypertension and increases susceptibility for the development of hypertension-induced microalbuminuria.
Prevalence and risk factors of hypertension following nephrectomy in living kidney donors
TLDR
The multivariate analysis showed that obesity at the time of donation was a risk factor for HTN and Obese donor [body mass index (BMI) ≥30)] has higher risk of HTN after nephrectomy than nonobese donor.
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References

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TLDR
Donor nephrectomy has minimal adverse effects on overall health status and regular donor follow-up identifies at-risk populations and potentially modifiable factors.
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TLDR
It is concluded that most kidney donors have normal renal function 20–37 years post donation, however, some do develop renal dysfunction; some, renal failure.
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Background. Living-donation kidney transplantation (LDKT) is increasingly performed for treatment of chronic renal failure. Recently, risks for the donor and problems in decision-making have been
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TLDR
On average, the remaining renal function of kidney donors did not deteriorate more rapidly than what may be expected from ageing, and the continued use of living kidney donors if strict criteria are used for acceptance.
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TLDR
Prospective registration of living kidney donors and prospective studies of diverse populations of donors are essential to protect living donors and preserve living-kidney donation.
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Although kidneys from living donors provide the best functional outcome, 50% of potential candidates must be excluded, and a thorough evaluation of potential donors is necessary.
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TLDR
It is demonstrated that the function of the solitary kidney is not adversely affected by prolonged compensatory hyperfiltration, although there appears to be an increased prevalence of microalbuminuria and hypertension.
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TLDR
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TLDR
Living donation as practiced for the past 50 yr has been safe with minimal immediate and long-term risk for the donor, but the future experience may not be the same as the authors' society is becoming increasingly obese and developing associated health problems.
Long-term follow-up of 102 living kidney donors.
TLDR
The utilization of living donors for kidney transplantation, an option which helps broaden a limited donor pool, is supported by the evaluation of living-related kidney donors.
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