Long‐term, intermittent treatment of chronic hand eczema with mometasone furoate

@article{Veien1999LongtermIT,
  title={Long‐term, intermittent treatment of chronic hand eczema with mometasone furoate},
  author={Niels Kren Veien and P {\O}lholm Larsen and Kristian thestrup-pedersen and Geert Schou},
  journal={British Journal of Dermatology},
  year={1999},
  volume={140}
}
Chronic hand eczema can be incapacitating, and there is little knowledge of the efficacy and safety of long‐term treatment with topical corticosteroids. We compared the efficacy and safety of two different schedules for the treatment of chronic hand eczema with a potent topical corticosteroid, mometasone furoate. In a prospective, open, randomized trial, 120 patients with chronic hand eczema were treated daily with mometasone furoate fatty cream until the dermatitis cleared or for a maximum of… Expand
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References

SHOWING 1-10 OF 17 REFERENCES
Intermittent maintenance therapy in chronic hand eczema with clobetasol propionate and flupredniden acetate.
TLDR
It is suggested that an intermittent schedule is advantageous when using a corticosteroid of high potency when keeping the dermatitis in remission. Expand
Comparison of cyclosporine and topical betamethasone-17,21-dipropionate in the treatment of severe chronic hand eczema.
TLDR
Low-dose cyclosporine at 3 mg/kg/day is as effective as topical BDP in the treatment of chronic hand Eczema and could be useful as an alternative treatment for severe chronic hand eczema in patients unresponsive to conventional treatment. Expand
Chronic eczematous dermatitis of the hands: a comparison of PUVA and UVB treatment.
TLDR
PUVA and UVB treatments are alternative treatment modalities in patients with recalcitrant chronic eczematous dermatitis of the hands and PUVA is superior to UVB. Expand
Steroid-Induced Dermal Atrophy
TLDR
The results of the investigation presented here show that thinning of the skin must also be expected with discontinuous application of topical CS. Expand
Steroid-induced dermal atrophy. Investigations on discontinuous application.
TLDR
The results of the investigation presented here show that thinning of the skin must also be expected with discontinuous application of topical CS. Expand
A double‐blind study of Grenz ray therapy in chronic eczema of the hands
TLDR
There was a significantly better response to active treatment 5 and 10 weeks after the start of treatment compared with the untreated control, and active treatment to one hand while the other, which received simulated therapy, served as a control. Expand
Recovery of human skin collagen synthesis after short‐term topical corticosteroid treatment and comparison between young and old subjects
TLDR
Indicating that collagen synthesis is not completely normalized in the human skin even during a 2‐week corticoid‐free period, collagen synthesis was recovered to about 50% of the level seen in the non‐treated skin. Expand
Epidemiology of hand eczema in an industrial city.
  • B. Meding
  • Medicine
  • Acta dermato-venereologica. Supplementum
  • 1990
TLDR
A multiple logistic regression analysis revealed that the most important predictive factor for hand eczema was female sex, followed by occupational exposure, a history of asthma and/or hayfever and a service occupation, which was shown to be a long-lasting disease with a relapsing course. Expand
Tachyphylaxis to Topical Steroid Measured by Histamine‐induced Wheal Suppression
TLDR
Ten healthy volunteers were studied and there was practically total tolerance to topical steroid, which showed minimal suppression of histamine wheal formation, which confirms the occurrence of the phenomenon of tachyphylaxis by different experimental techniques. Expand
Tachyphylaxis to histamine-induced wheal suppression by topical 0.05% clobetasol propionate in normal versus croton oil-induced dermatitic skin.
TLDR
Time courses of tachyphylaxis to the action of 0.05% clobetasol propionate were significantly different in normal skin and dermatitic skin, and complete tolerance occurred earlier in dermatiticskin compared to normal skin. Expand
...
1
2
...