Long‐Term Outcomes of Patent Foramen Ovale Closure or Medical Therapy after Stroke

@article{Saver2017LongTermOO,
  title={Long‐Term Outcomes of Patent Foramen Ovale Closure or Medical Therapy after Stroke},
  author={J. Saver and J. Carroll and D. Thaler and R. Smalling and Lee A MacDonald and D. Marks and D. Tirschwell},
  journal={The New England Journal of Medicine},
  year={2017},
  volume={377},
  pages={1022–1032}
}
  • J. Saver, J. Carroll, +4 authors D. Tirschwell
  • Published 2017
  • Medicine
  • The New England Journal of Medicine
  • BACKGROUND Whether closure of a patent foramen ovale reduces the risk of recurrence of ischemic stroke in patients who have had a cryptogenic ischemic stroke is unknown. METHODS In a multicenter, randomized, open‐label trial, with blinded adjudication of end‐point events, we randomly assigned patients 18 to 60 years of age who had a patent foramen ovale (PFO) and had had a cryptogenic ischemic stroke to undergo closure of the PFO (PFO closure group) or to receive medical therapy alone (aspirin… CONTINUE READING
    412 Citations
    Patent Foramen Ovale Closure in the Setting of Cryptogenic Stroke: A Meta-Analysis of Five Randomized Trials.
    • L. Garg, A. Haleem, +7 authors B. Kluck
    • Medicine
    • Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
    • 2018
    • 3
    The Case for Selective Patent Foramen Ovale Closure After Cryptogenic Stroke
    • 7
    Patent foramen ovale closure vs. medical therapy for cryptogenic stroke: a meta-analysis of randomized controlled trials
    • 49
    • PDF

    References

    SHOWING 1-10 OF 27 REFERENCES
    Closure of patent foramen ovale versus medical therapy after cryptogenic stroke.
    • 702
    • PDF
    Closure or medical therapy for cryptogenic stroke with patent foramen ovale.
    • 771
    • PDF
    Percutaneous closure of patent foramen ovale in cryptogenic embolism.
    • 651
    • PDF
    Device Closure of Patent Foramen Ovale After Stroke: Pooled Analysis of Completed Randomized Trials.
    • 147
    • PDF
    Very long-term follow-up after percutaneous closure of patent foramen ovale.
    • 14
    Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk Patients.
    • 2,374
    • PDF