Loneliness in late-life depression: structural and functional connectivity during affective processing.

@article{Wong2016LonelinessIL,
  title={Loneliness in late-life depression: structural and functional connectivity during affective processing.},
  author={N. M. Wong and H. Liu and C. Lin and C-M. Huang and Y-Y Wai and S. Lee and T. M. Lee},
  journal={Psychological medicine},
  year={2016},
  volume={46 12},
  pages={
          2485-99
        }
}
BACKGROUND Late-life depression (LLD) in the elderly was reported to present with emotion dysregulation accompanied by high perceived loneliness. Previous research has suggested that LLD is a disorder of connectivity and is associated with aberrant network properties. On the other hand, perceived loneliness is found to adversely affect the brain, but little is known about its neurobiological basis in LLD. The current study investigated the relationships between the structural connectivity… Expand
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