Loneliness and stress-related inflammatory and neuroendocrine responses in older men and women.

@article{Hackett2012LonelinessAS,
  title={Loneliness and stress-related inflammatory and neuroendocrine responses in older men and women.},
  author={Ruth A Hackett and Mark Hamer and Romano Endrighi and Lena Brydon and Andrew Steptoe},
  journal={Psychoneuroendocrinology},
  year={2012},
  volume={37 11},
  pages={1801-9}
}
Loneliness is a predictor of mortality and increased cardiovascular morbidity. Inflammation is a potential pathway through which loneliness might impact health. The aim of the study was to investigate the relationship between loneliness and inflammatory interleukin-6 (IL-6), interleukin-1 receptor antagonist (IL-1Ra) and monocyte chemotactic protein-1 (MCP-1) responses to standardized mental stress. A secondary purpose was to evaluate whether individual variations in cortisol responses… CONTINUE READING
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