Lola regulates midline crossing of CNS axons in Drosophila.

@article{Crowner2002LolaRM,
  title={Lola regulates midline crossing of CNS axons in Drosophila.},
  author={Daniel Crowner and Knut Madden and Scott C. Goeke and Edward Giniger},
  journal={Development},
  year={2002},
  volume={129 6},
  pages={1317-25}
}
The pattern and level of expression of axon guidance proteins must be choreographed with exquisite precision for the nervous system to develop its proper connectivity. Previous work has shown that the transcription factor Lola is required for central nervous system (CNS) axons of Drosophila to extend longitudinally. We show here that Lola is simultaneously required to repel these same longitudinal axons away from the midline, and that it acts, in part, by augmenting the expression both of the… CONTINUE READING

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