Logistic time constant of isovolumic relaxation pressure-time curve in the canine left ventricle. Better alternative to exponential time constant.

@article{Matsubara1995LogisticTC,
  title={Logistic time constant of isovolumic relaxation pressure-time curve in the canine left ventricle. Better alternative to exponential time constant.},
  author={Hisahiro Matsubara and Miyako Takaki and Shuichiro Yasuhara and Junichi Araki and Hiroyuki Suga},
  journal={Circulation},
  year={1995},
  volume={92 8},
  pages={2318-26}
}
BACKGROUND The time constant of left ventricular (LV) relaxation derived from a monoexponential model has been widely used as an index of LV relaxation rate or lusitropism, although this model has several well-recognized problems. In the present study, we proposed a logistic model and derived a "logistic" time constant (TL) as a better alternative to the conventional "exponential" time constant (TE). METHODS AND RESULTS A total of 189 beats (147 isovolumic and 42 ejecting beats) were… CONTINUE READING