Logistic regression model to estimate the risk of unbalanced offspring in reciprocal translocations

@article{Cans1993LogisticRM,
  title={Logistic regression model to estimate the risk of unbalanced offspring in reciprocal translocations},
  author={Christine Cans and Olivier Cohen and C. Lavergne and Marie-Ange Mermet and Jacques Demongeot and Pierre Jalbert},
  journal={Human Genetics},
  year={1993},
  volume={92},
  pages={598-604}
}
The aim of this study was to estimate the risk of viable unbalanced offspring for a parental carrier of reciprocal translocation. On a large computerized database of reciprocal translocations we used logistic regression to model this risk. The status of the progeny is the outcome variable. Explanatory covariates are cytogenetic characteristics of the translocation, age and sex of the parental carrier, and potential viability of the gametes. The results obtained by the logistic model demonstrate… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 39 references

Unbalances of reciprocal translocations (rcp): maximum thresholds of viability

  • P Jalbert, O Cohen, C Cans, MA Mermet, J Demongeot
  • Am J Hum Genet
  • 1992
1 Excerpt

Applied logistic regression

  • DW Hosmer, S Lemeshow
  • 1989
1 Excerpt

The simple reciprocal translocation

  • RJM Gardner, GS Sutherland
  • Scriver C (eds) Oxford monographs on medical…
  • 1989
1 Excerpt

Collaborative USA data on prenatal diagnosis for parental carriers of chromosome rearrangements : risk of unbalanced progeny

  • A Daniel
  • The cytogenetics of mammalian autosomal…
  • 1988

Collaborative USA data on prenatal diagnosis for parental carriers of chromosome rearrangements: risk of unbalanced progeny. In: Daniel A (ed) The cytogenetics of mammalian autosomal rearrangements

  • A Daniel, EB Hook, G Wulf
  • 1988
2 Excerpts

Similar Papers

Loading similar papers…