Logic of the yeast metabolic cycle: temporal compartmentalization of cellular processes.

@article{Tu2005LogicOT,
  title={Logic of the yeast metabolic cycle: temporal compartmentalization of cellular processes.},
  author={Benjamin Pang-hsien Tu and Andrzej Kudlicki and Maga Rowicka and Steven L. McKnight},
  journal={Science},
  year={2005},
  volume={310 5751},
  pages={1152-8}
}
Budding yeast grown under continuous, nutrient-limited conditions exhibit robust, highly periodic cycles in the form of respiratory bursts. Microarray studies reveal that over half of the yeast genome is expressed periodically during these metabolic cycles. Genes encoding proteins having a common function exhibit similar temporal expression patterns, and genes specifying functions associated with energy and metabolism tend to be expressed with exceptionally robust periodicity. Essential… CONTINUE READING
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