Logic and justification for dimensional assessment of symptoms and related clinical phenomena in psychosis: Relevance to DSM-5

@article{Barch2013LogicAJ,
  title={Logic and justification for dimensional assessment of symptoms and related clinical phenomena in psychosis: Relevance to DSM-5},
  author={Deanna M. Barch and Juan R. Bustillo and Wolfgang Gaebel and Raquel E. Gur and Stephan Heckers and Dolores Malaspina and Michael J. Owen and Susan K. Schultz and Rajiv Tandon and Ming T. Tsuang and Jim van Os and William T Carpenter},
  journal={Schizophrenia Research},
  year={2013},
  volume={150},
  pages={15-20}
}
Work on the causes and treatment of schizophrenia and other psychotic disorders has long recognized the heterogeneity of the symptoms that can be displayed by individuals with these illnesses. Further, researchers have increasingly emphasized the ways in which the severity of different symptoms of this illness can vary across individuals, and have provided evidence that the severity of such symptoms can predict other important aspects of the illness, such as the degree of cognitive and/or… Expand
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References

SHOWING 1-10 OF 91 REFERENCES
The genetic deconstruction of psychosis.
TLDR
Understanding of the brain mechanisms that link specific gene actions and products to the subjective experience of psychopathological symptoms is likely to be bridged by employing intermediate (or endo-) phenotypes in the domains such as cognition, neurophysiology, or neuroanatomy rather than relying upon clinical measures alone. Expand
Schizophrenia, “just the facts” 4. Clinical features and conceptualization
TLDR
Heterogeneity in the etiopathology, symptomatology, and course of schizophrenia can be addressed by a dimensional approach to psychopathology, a clinical staging approach to illness course, and by elucidating endophenotypes and markers of illness progression, respectively. Expand
Schizoaffective disorder: diagnostic issues and future recommendations.
TLDR
Schizoaffective disorder is a prototypic boundary condition that epitomizes the pitfalls of the current categorical classification system and should be omitted in future revisions of DSM, allowing the development of meaningful nomenclature that rests upon further rigorous investigation of differences and similarities between disorders. Expand
How many and which are the psychopathological dimensions in schizophrenia? Issues influencing their ascertainment
TLDR
The present paper reviews the main methodological issues which have led to the current confusion about the number of dimensions underlying schizophrenic psychopathology and proposes a hierarchical approach for organizing the complex dimensional structure of schizophrenic symptoms. Expand
Empirical validation of primary negative symptoms: independence from effects of medication and psychosis.
TLDR
Two factors, termed affective flattening and diminished motivation, exhibited similar loadings when the patients were both on and off medication, and this finding will aid in the identification of primary negative symptoms. Expand
Exploring the borders of the schizoaffective spectrum: a categorical and dimensional approach.
TLDR
The overall association pattern of illness-related variables with mood and psychotic syndromes was largely independent of specific diagnostic categories, and the dimensional approach was neatly superior to the traditional diagnostic approach in explaining the characteristics of the illness. Expand
Neuropsychological symptom dimensions in bipolar disorder and schizophrenia.
TLDR
Together, these data suggest that while the same underlying factor structure describes NP functioning in both groups, the profile of impairments appears to vary with the diagnosis. Expand
Neuropsychological function and dysfunction in schizophrenia and psychotic affective disorders.
TLDR
Differences in NP performance between schizophrenia and psychotic affective disorders are largely quantitative, and a significant minority of schizophrenia patients are NP normal. Expand
Comparing clinical and neurocognitive features of the schizophrenia prodrome to the bipolar prodrome
TLDR
Preliminary support is provided for a bipolar prodrome, which may be indistinguishable from the schizophrenia prodrome based on clinical and neurocognitive measures currently used in high-risk schizophrenia programs. Expand
The NIMH-MATRICS consensus statement on negative symptoms.
TLDR
A consensus development conference was held to review the data relating to the existence of separate domains within negative symptoms, as a prerequisite for choosing appropriate measures of these domains in clinical trials and to examine issues that may interfere with treatment development. Expand
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