Locus coeruleus is a central chemoreceptive site in toads.

  title={Locus coeruleus is a central chemoreceptive site in toads.},
  author={Carolina R Noronha-de-Souza and K{\^e}nia C B{\'i}cego and Gustavo Trindade Michel and Mogens Lesner Glass and Luiz Guilherme Siqueira Branco and Luciane H Gargaglioni},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  volume={291 4},
The locus coeruleus (LC) has been suggested as a CO2 chemoreceptor site in mammals. This nucleus is a mesencephalic structure of the amphibian brain and is probably homologous to the LC in mammals. There are no data available for the role of LC in the central chemoreception of amphibians. Thus the present study was designed to investigate whether LC of toads (Bufo schneideri) is a CO2/H+ chemoreceptor site. Fos immunoreactivity was used to verify whether the nucleus is activated by hypercarbia… CONTINUE READING