Locus coeruleus and neuronal plasticity in a model of focal limbic epilepsy.

Abstract

PURPOSE A lesion of the noradrenergic nucleus Locus Coeruleus (LC) converts sporadic seizures evoked by microinfusion of bicuculline into the anterior piriform cortex (APC) of rats into limbic status epilepticus (SE). The purpose of this study was to evaluate the chronic effects of this new model of SE on the onset of secondary epileptogenesis. We further… (More)

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Cite this paper

@article{Giorgi2006LocusCA, title={Locus coeruleus and neuronal plasticity in a model of focal limbic epilepsy.}, author={Fillippo Sean Giorgi and Giuseppe Mauceli and Fabio Blandini and Stefano Ruggieri and Antonio Paparelli and L. Murri and Francesco Fornai}, journal={Epilepsia}, year={2006}, volume={47 Suppl 5}, pages={21-5} }