Locus coeruleus activation shortens synaptic drive while decreasing spike latency and jitter in sensorimotor cortex. Implications for neuronal integration.

@article{Lecas2004LocusCA,
  title={Locus coeruleus activation shortens synaptic drive while decreasing spike latency and jitter in sensorimotor cortex. Implications for neuronal integration.},
  author={J C Lecas},
  journal={The European journal of neuroscience},
  year={2004},
  volume={19 9},
  pages={2519-30}
}
  • J C Lecas
  • Published 2004 in The European journal of neuroscience
Chronic recording of locus coeruleus (LC) neurons in rat and monkey have pointed out that brief, phasic LC discharges, but not sustained activity, are specifically related to salient stimuli and attention. However, the sensory consequences of phasic activation of the noradrenergic system by a brief conditioning stimulation of the LC have not been fully investigated. This study examined the effect of LC activation on synaptic and neuronal responses to a tactile stimulus in the sensorimotor… CONTINUE READING

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