Locoregional therapy for cholangiocarcinoma

  title={Locoregional therapy for cholangiocarcinoma},
  author={Jan B. Kuhlmann and H. E. Blum},
  journal={Current Opinion in Gastroenterology},
Purpose of review Cholangiocarcinoma has a poor prognosis. Surgical resection offers the only curative option and usually requires a major hepatic resection in addition to resection of the cholangiocarcinoma. Unfortunately, curative resection is possible in only about 30% of patients due to locally advanced disease, distant metastases or comorbidity in elderly patients. Even after resection, the recurrence rate is approximately 60%, resulting in a low 5-year overall survival (OS). In… 

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