Locoregional first recurrence after mastectomy: prospective cohort studies with and without immediate chemotherapy.

@article{Haylock2000LocoregionalFR,
  title={Locoregional first recurrence after mastectomy: prospective cohort studies with and without immediate chemotherapy.},
  author={Brian J. Haylock and Christopher M.L. Coppin and John Morris Jackson and Vivien E. Basco and KennethS. Wilson},
  journal={International journal of radiation oncology, biology, physics},
  year={2000},
  volume={46 2},
  pages={
          355-62
        }
}
PURPOSE To evaluate prospectively the impact of combination chemotherapy in the combined modality treatment of isolated first locoregional recurrence (LRR) following mastectomy for breast cancer. METHODS AND MATERIALS Between 1979 and 1989, 120 chemotherapy-naive women with isolated LRR as first failure after mastectomy were prospectively identified, uniformly staged, and systematically followed. Treatment consisted of excision if feasible, radical locoregional radiotherapy, and a hormonal… CONTINUE READING
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