Locomotory patterns, spatiotemporal organization of exploration and spatial memory in serotonin transporter knockout mice

@article{Kalueff2007LocomotoryPS,
  title={Locomotory patterns, spatiotemporal organization of exploration and spatial memory in serotonin transporter knockout mice},
  author={Allan V Kalueff and Catherine L. Jensen and DennisL. Murphy},
  journal={Brain Research},
  year={2007},
  volume={1169},
  pages={87-97}
}
Serotonin transporter knockout (SERT-/-) mice are extensively used as a genetic model of several neuropsychiatric disorders, and consistently display anxiety-like behaviors and inactivity in different tests. To better understand how these mice organize their behavior, we assessed the open field and elevated plus maze spatiotemporal patterning of activity in adult male SERT wild type (+/+), heterozygous (+/-) and -/- mice on C57BL/6J genetic background using new videotracking and analytic… CONTINUE READING
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