Locomotor and sensorimotor performance deficit in rats following exposure to pyridostigmine bromide, DEET, and permethrin, alone and in combination.

@article{AbouDonia2001LocomotorAS,
  title={Locomotor and sensorimotor performance deficit in rats following exposure to pyridostigmine bromide, DEET, and permethrin, alone and in combination.},
  author={Mohamed Bahie Abou-Donia and Larry B. Goldstein and Katherine Heard Jones and Ali Abdelzaher Abdel-Rahman and Tirupapuliyur V. Damodaran and Anjelika M. Dechkovskaia and Sarah L. Bullman and Baharak Amir and Wasiuddin A. Khan},
  journal={Toxicological sciences : an official journal of the Society of Toxicology},
  year={2001},
  volume={60 2},
  pages={305-14}
}
Since their return from Persian Gulf War (PGW), many veterans have complained of symptoms including muscle and joint pain, ataxia, chronic fatigue, headache, and difficulty with concentration. The causes of the symptoms remain unknown. Because these veterans were exposed to a combination of chemicals including pyridostigmine bromide (PB), DEET, and permethrin, we investigated the effects of these agents, alone and in combination, on the sensorimotor behavior and central cholinergic system of… CONTINUE READING

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