Locomotor and pyretic effects of MDMA-ethanol associations in rats.

  title={Locomotor and pyretic effects of MDMA-ethanol associations in rats.},
  author={J. C. Cassel and H{\'e}l{\`e}ne Jeltsch and Julie Koenig and Byron C Jones},
  volume={34 2-3},
3,4-Methylenedioxymethamphetamine [(MDMA) or ecstasy] is a popular club drug often used in combination with ethanol. In the current study, we investigated the effects of MDMA and ethanol combinations on locomotor activity and body temperature of rats. For four consecutive days, male Long-Evans rats were treated daily with a 10-mg/kg dose of MDMA with or without a 1.5-g/kg dose of ethanol. 3,4-Methylenedioxymethamphetamine increased spontaneous activity (on average +1,140%), and this increase… CONTINUE READING

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