Loco-regional treatments in first-diagnosis glioblastoma: literature review on association between Stupp protocol and Gliadel

@article{Salmaggi2011LocoregionalTI,
  title={Loco-regional treatments in first-diagnosis glioblastoma: literature review on association between Stupp protocol and Gliadel},
  author={Andrea Salmaggi and Stefania Duri and Antonio Silvani and Paola Gaviani and Ida Maddalena Milanesi and Cecilia Casali and Francesco Di Meco},
  journal={Neurological Sciences},
  year={2011},
  volume={32},
  pages={241-245}
}
Loco-regional chemotherapy with carmustine wafers (Gliadel) positioned at surgery and followed by radiotherapy has been shown to prolong survival in first-diagnosis glioblastoma, as well as concomitant radiochemotherapy with temozolomide. The combination of Gliadel with the Stupp protocol has mostly been investigated in retrospective studies. objective of… CONTINUE READING