Location of genes in chromosomes: Random or not?


The possibility is discussed that the order of genes in chromosomes is not random but determined by natural selection, i.e., is a selectively valuable character. Cases of long-term conservation of gene linkage or synteny in evolution are presented. Examples and possible mechanisms of nonrandom gene localization in prokaryotic and eukaryotic chromosomes are considered.

DOI: 10.1134/S1022795410100066

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@article{Zakharov2010LocationOG, title={Location of genes in chromosomes: Random or not?}, author={Ilia A. Zakharov}, journal={Russian Journal of Genetics}, year={2010}, volume={46}, pages={1165-1172} }