Locally balanced dendritic integration by short-term synaptic plasticity and active dendritic conductances.

@article{Volman2009LocallyBD,
  title={Locally balanced dendritic integration by short-term synaptic plasticity and active dendritic conductances.},
  author={Vladislav Volman and Herbert Levine and Eshel Ben-Jacob and Terrence J. Sejnowski},
  journal={Journal of neurophysiology},
  year={2009},
  volume={102 6},
  pages={3234-50}
}
The high degree of variability observed in spike trains and membrane potentials of pyramidal neurons in vivo is thought to be a consequence of a balance between excitatory and inhibitory inputs, which depends on the dynamics of the network. We simulated synaptic currents and ion channels in a reconstructed hippocampal CA1 pyramidal cell and show here that a local balance can be achieved on a dendritic branch with a different mechanism, based on presynaptic depression of quantal release… CONTINUE READING