Localized scleroderma.

@article{Kreuter2012LocalizedS,
  title={Localized scleroderma.},
  author={Alexander Kreuter},
  journal={Dermatologic therapy},
  year={2012},
  volume={25 2},
  pages={135-47}
}
Localized scleroderma (also called morphea) is a term encompassing a spectrum of sclerotic autoimmune diseases that primarily affect the skin, but also might involve underlying structures such as the fat, fascia, muscle, and bones. Its exact pathogenesis is still unknown, but several trigger factors in genetically predisposed individuals might initially lead to an immunologically triggered release of pro-inflammatory cytokines, resulting in a profound dysregulation of the connective tissue… CONTINUE READING
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