Localized permanent epidemics: the genesis of chloroquine resistance in Plasmodium falciparum.

  • J Verdrager
  • Published 1995 in
    The Southeast Asian journal of tropical medicine…


Localized permanent epidemics occur when, for an indefinite period of time, there is a temporary but continuous introduction of unprotected non-immunes into the same locality of a hyperendemic area. The main epidemiological factors involved in the genesis of localized permanent epidemics were encountered in Pailin (Cambodia) the epicenter of drug resistance… (More)


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