Localized in vivo 13C NMR spectroscopy of the brain.

  title={Localized in vivo 13C NMR spectroscopy of the brain.},
  author={Rolf Gruetter and Gregor Adriany and In-Young Choi and P E Henry and Hongxia Lei and G{\"u}lin Oz},
  journal={NMR in biomedicine},
  volume={16 6-7},
Localized (13)C NMR spectroscopy provides a new investigative tool for studying cerebral metabolism. The application of (13)C NMR spectroscopy to living intact humans and animals presents the investigator with a number of unique challenges. This review provides in the first part a tutorial insight into the ingredients required for achieving a successful implementation of localized (13)C NMR spectroscopy. The difficulties in establishing (13)C NMR are the need for decoupling of the one-bond (13… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 78 extracted citations

In vivo 13C MRS in the mouse brain at 14.1 Tesla and metabolic flux quantification under infusion of [1,6-13C2]glucose.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism • 2018


Publications referenced by this paper.
Showing 1-10 of 177 references

Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activity.

Proceedings of the National Academy of Sciences of the United States of America • 1998
View 5 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…