Localized delivery of growth factors for bone repair.

  title={Localized delivery of growth factors for bone repair.},
  author={Vera Luginbuehl and Lorenz Meinel and Hans Peter Merkle and Bruno A Gander},
  journal={European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V},
  volume={58 2},
Delivery of growth factors for tissue (e.g. bone, cartilage) or cell repair (e.g. nerves) is about to gain important potential as a future therapeutic tool. Depending on the targeted cell type and its state of differentiation, growth factors can activate or regulate a variety of cellular functions. Therefore, strictly localized delivery regimens at well-defined kinetics appear to be logical prerequisites to assure safe and efficacious therapeutic use of such factors and avoid unwanted side… CONTINUE READING

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