Localized alteration of microtubule polymerization in response to guidance cues.

@article{Kelly2010LocalizedAO,
  title={Localized alteration of microtubule polymerization in response to guidance cues.},
  author={Terri-Ann N Kelly and Yasuhiro Katagiri and Keri B. Vartanian and Pramukta Kumar and Inn-Inn Chen and William J. Rosoff and Jeffery S Urbach and Herbert M Geller},
  journal={Journal of neuroscience research},
  year={2010},
  volume={88 14},
  pages={3024-33}
}
Inhibition of microtubule dynamic instability prevents growth cone turning in response to guidance cues, yet specific changes in microtubule polymerization as growth cones encounter boundaries have not been investigated. In this study, we examined the rate and direction of microtubule polymerization in response to soluble nerve growth factor (NGF) and… CONTINUE READING