Localization patterns of the ganglioside GM1 in human sperm are indicative of male fertility and independent of traditional semen measures

@inproceedings{Cardona2017LocalizationPO,
  title={Localization patterns of the ganglioside GM1 in human sperm are indicative of male fertility and independent of traditional semen measures},
  author={Cristina Cardona and Queenie V. Neri and Alana J Simpson and Melissa A Moody and G. Charles Ostermeier and Eric K Seaman and Theodore Paniza and Zev Rosenwaks and Gianpiero D. Palermo and Alexander J Travis},
  booktitle={Molecular reproduction and development},
  year={2017}
}
Semen analysis lacks a functional component and best identifies extreme cases of infertility. The ganglioside GM1 is known to have functional roles during capacitation and acrosome exocytosis. Here, we assessed whether GM1 localization patterns (Cap-Score™) correspond with male fertility in different settings: Study 1 involved couples pursuing assisted reproduction in a tertiary care fertility clinic, while Study 2 involved men with known fertility versus those questioning their fertility at a… CONTINUE READING
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Localization patterns of the ganglioside GM1 in human sperm are indicative of male fertility and independent of traditional semen

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