Localization of thrombospondin and its cysteine-serine-valine-threonine-cysteine-glycine-specific receptor in human breast carcinoma.


BACKGROUND Thrombospondin (TSP), a cell-matrix adhesion protein, and cysteine-serine-valine-threonine-cysteine-glycine (CSVTCG), a major TSP cell adhesive domain, have recently been shown to play a role in tumor cell metastasis. In this study we immunohistochemically localized TSP and its newly discovered CSVTCG-specific receptor in normal, benign, and… (More)


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