Localization of the tandem pore domain K+ channel TASK-1 in the rat central nervous system.

@article{Kindler2000LocalizationOT,
  title={Localization of the tandem pore domain K+ channel TASK-1 in the rat central nervous system.},
  author={Christoph H. Kindler and Christian Pietruck and Charles Spencer Yost and Erik R. Sampson and Andrew T. Gray},
  journal={Brain research. Molecular brain research},
  year={2000},
  volume={80 1},
  pages={99-108}
}
Recently, a new family of potassium channels with two pore domains in tandem and four transmembrane segments has been identified. Seven functional mammalian channels have been reported at this time. These channels give rise to baseline potassium currents because they are not gated by voltage and exhibit spontaneous activity at all membrane potentials. Although the physiological role of these ion channels has yet to be determined, three mammalian members of this family (TREK-1, TASK-1, TASK-2… CONTINUE READING

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